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Can polycythemia cause hypoglycemia?

Can polycythemia cause hypoglycemia?

In symptomatic newborns polycythemia may affect many organs and systems. Hyperviscosity, decrease of tissue perfusion, and metabolic complications such as hypoglycemia and hypocalcemia are responsible for clinical signs [10,32].

Why does polycythemia cause hypoglycemia?

As blood flow is further reduced, occlusion of small vessels may result in ischemia and consumption of platelets. Because glucose is transported mainly in plasma and relative plasma volume is decreased, the decreased blood flow can result in hypoglycemia.

Why does the IDM infant with polycythemia require adequate hydration?

Treatment of Polycythemia in the Newborn If the newborn has no symptoms, fluids for hydration are given by vein because dehydration. Dehydration occurs when there is significant loss of body water and, to varying amounts, electrolytes… read more (fluid loss) can make the blood even thicker.

Does polycythemia go away in newborn?

In most cases, polycythemia has no lasting effects. As the extra red blood cells break down, the baby will probably have yellowing of the skin (jaundice) for a short time. This is normal.

What is neonatal polycythemia?

Neonatal polycythemia is characterized by a venous hematocrit (hct) that greatly exceeds normal values for gestational and postnatal age. This condition affects approximately 1 to 5 percent of newborns.

How common is polycythemia in newborns?

Genetic disorders, such as trisomy 13, trisomy 18, trisomy 21, and Beckwith-Wiedemann syndrome. The incidence of polycythemia in infants who have Down syndrome is 15% to 33%.

Does polycythemia affect blood sugar?

Keep in mind that whole blood glucose values may be spuriously low in polycythemia rubra vera because of the unequal distribution of glucose between erythrocytes and plasma, excessive glycolysis by erythrocytes, or both.

What are normal blood sugar levels for newborns?

The normal range of blood glucose is around 1.5–6 mmol/l in the first days of life, depending on the age of the baby, type of feed, assay method used, and possibly the mode of delivery. Up to 14% of healthy term babies may have blood glucose less than 2.6 mmol/l in the first three days of life.

Why is there polycythemia in GDM babies?

Polycythaemia is an important problem that is observed in some infants born to diabetic mothers: fetal hyperinsulinaemia and elevated Epo levels, due to intrauterine chronic hypoxia, may cause polycythaemia in these infants.

What is hypoglycemia in a newborn?

A low blood sugar level in newborn babies is also called neonatal hypoglycemia. It refers to low blood sugar (glucose) in the first few days after birth.

What causes high hematocrit in newborns?

Diabetes in the baby’s birth mother. Inherited diseases and genetic problems. Too little oxygen reaching body tissues (hypoxia) Twin-twin transfusion syndrome (occurs when blood moves from one twin to the other)

How to manage neonatal asymptomatic polycythaemia?

The management of neonatal asymptomatic polycythaemia is disputable; this is because of the absence of proof showing that forceful treatment upgrades long haul results. Before a conclusion of polycythaemia is made, it is obligatory to rule out dehydration and somewhat hypoglycemia [2].

What is hypoglycemia in newborns?

Hypoglycemia is the most common metabolic disturbance occurring in the neonatal period. Screening at-risk infants and the management of low blood glucose levels in the first hours to days of life is a frequent issue in the care of the newborn infant.

What are the PES guidelines for hypoglycemia in newborns?

Per the PES guidelines, infants unable to maintain pre-prandial blood glucose values >50 mg/dL in the first 48 hours of life or >60 mg/dL thereafter are at risk for persistent hypoglycemia and require further workup prior to discharge home.[4]

What is the incidence of polycythemia in neonates born at SGA?

The incidence of polycythemia is 15% among term SGA infants as compared to 2% in term appropriate for gestational age (AGA) infants6. Neonates born to mothers at high altitudes also have a higher incidence of polycythemia1. Polycythemia is unlikely to occur in neonates born at a gestational age less than 34 weeks1.

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