Is benzophenone 3 a carcinogen?
Benzophenone is a mutagen, carcinogen, and endocrine disruptor. Its presence in food products or food packaging is banned in the United States.
What is NTP in safety?
The National Toxicology Program (NTP) is a unit of the U.S. Department of Health and Human Services. NTP coordinates toxicology research and testing activities within the Department and provides information about potentially toxic chemicals to regulatory and research agencies and the public.
Is benzophenone mutagenic?
Benzophenone was not mutagenic in S. typhimurium strain TA98, TA100, TA1535, or TA1537, with or without S9 activation, and it did not induce micronuclei in bone marrow erythrocytes of male mice administered benzophenone by intraperitoneal injection.
Is benzophenone-4 safe in hand sanitizer?
Safety Information In addition, a Cosmetic Ingredient Review (CIR) expert scientific panel states that benzophenone and its derivatives (benzophenone-1, -3, -4, -5, -9 and -11) are safe as typically used in cosmetics and personal care products.
Is benzophenone safe in sunscreen?
Unlike many other chemical sunscreens, it is highly stable but its UV absorbing abilities are weak so it always has to be combined with other sunscreen agents for proper protection. More often than not, it’s used as a photostabilizer rather than a proper sunscreen agent as it can protect formulas nicely from UV damage.
Is benzophenone-3 the same as benzophenone?
What is benzophenone? Benzophenone is a chemical with a sweet floral smell. Benzophenone is a different chemical than benzophenone-3 (also called oxybenzone) and benzophenone-4 (also called sulisobenzone).
Is benzophenone-3 safe to use?
What is the value of temperature at NTP?
20 °C
NIST uses a temperature of 20 °C (293.15 K, 68 °F) and an absolute pressure of 1 atm (14.696 psi, 101.325 kPa). This standard is also called normal temperature and pressure (abbreviated as NTP).
Who funds the NTP?
The National Toxicology Program (NTP) is an inter-agency program run by the United States Department of Health and Human Services to coordinate, evaluate, and report on toxicology within public agencies. The National Toxicology Program is headquartered at the National Institute of Environmental Health Sciences (NIEHS).
What is benzophenone oxime?
BENZOPHENONE OXIME a reagent for the colorimetric determination of urea and ureido compounds. Oxime is used as a ligand in transition-metal complex catalyst chemistry. Oxime acts as an antioxidant, radical scavenger which find applications in textile, plastic, paint, detergent, and rubber industry.
What is the NTP Tox for benzophenone?
Benzophenone, NTP TOX 61 B-3 T ABLE B1 Hematology Data for Rats in the 14-Week Feed Study of Benzophenone 0 ppm 1,250 ppm 2,500 ppm 5,000 ppm 10,000 ppm 20,000 ppm Male n Day 4 10 10 9 10 10 10 Day 22 10 10 10 10 10 10 Week 14 10 10 10 10 10 0 Monocytes (10 3 /µL) Day 4 0.12 ± 0.03 0.11 ± 0.02 0.06 ± 0.03
What are the target organs of benzophenone toxicity?
6 Benzophenone, NTP TOX 61 In rats, the liver and kidney were identified as target organs of benzophenone toxicity. Treatment-related increases in liver weights were attributed to hypertrophy and/or cytoplasmic vacuolization of hepatocytes.
What is the NOAEL for benzophenone toxicity in rats?
The kidney was also identified as a target organ of benzophenone toxicity in rats only, based on exposure concentration-related increases in kidney weights and microscopic changes. The NOAEL for benzophenone was not achieved in these studies. Benzophenone is not mutagenic in Salmonella 46 Benzophenone, NTP TOX 61 typhimurium
What are the uses of benzophenone?
Benzophenone is used as a photoinitiator, a fragrance enhancer, an ultraviolet curing agent, and, occasionally, as a flavor ingredient; it is also used in the manufacture of insecticides, agricultural chemicals, and pharmaceuticals and is an additive for plastics, coatings, and adhesives.