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What antibiotic covers Corynebacterium striatum?

What antibiotic covers Corynebacterium striatum?

Vancomycin should be used as the antibiotic of choice for the treatment of C. striatum infections, in monotherapy or in combination with piperacillin-tazobactam.

Does vancomycin cover Corynebacterium striatum?

striatum isolated from patients with chronic obstructive respiratory disease were susceptible to vancomycin too. Vancomycin is still active today and therefore it represents an adequate option for treatment of severe infections caused by C. striatum.

What is the drug of choice for endocarditis?

Treatment with aqueous penicillin or ceftriaxone is effective for most infections caused by streptococci. A combination of penicillin or ampicillin with gentamicin is appropriate for endocarditis caused by enterococci that are not highly resistant to penicillin.

What is the best treatment for endocarditis?

Many people with endocarditis are successfully treated with antibiotics. Sometimes, surgery may be needed to fix or replace damaged heart valves and clean up any remaining signs of the infection.

How do you treat corynebacteria?

The goal is both to kill the organism and to terminate toxin production. Many antibiotics are effective, including penicillin, erythromycin, clindamycin, rifampin, and tetracycline; erythromycin or penicillin is the treatment of choice and is usually given for 14 days.

What antibiotics cover Diphtheroids?

Penicillin, cephalothin, or erythromycin appear to be the agents of choice for the treatment of this kind of disease, although some strains of the organism may be resistant to them. Other antibiotics are also effective and should be used if those mentioned above fail to produce cure.

Does Levaquin cover Corynebacterium striatum?

In conclusion, levofloxacin was the most active of the six fluoroquinolones evaluated against coryneform bacteria isolated from clinical samples and could therefore be a promising treatment option in this setting.

Does doxycycline cover Corynebacterium striatum?

The susceptibilities of 265 strains of Corynebacterium species and other non-spore-forming gram-positive bacilli to 18 antimicrobial agents were tested. Most strains were susceptible to vancomycin, doxycycline, and fusidic acid.

When do you use aminoglycoside for synergy?

Synergy is needed with an aminoglycoside in order to achieve a bactericidal effect because most cell-wall active drugs are only considered bacteriostatic against enterococci. Of the two aminoglycosides used to treat enterococcal endocarditis, gentamicin is primarily used unless resistance is present.

How does aminoglycoside synergy work?

Mechanism of Synergy In combination with gentamicin or streptomycin, penicillin G and ampicillin facilitate the intracellular uptake of the aminoglycoside, which causes the subsequent bactericidal effect against the enterococci.

What is first line agent in patient with endocarditis?

First-line treatment: Cefepime 2 g IV q8h for normal renal function. Second-line treatment (if patient is penicillin or cephalosporin intolerant): Aztreonam 2 g IV q8h for normal renal function. Antipseudomonal penicillin plus aminoglycoside recommended if Pseudomonas aeruginosa endocarditis is suspected.

What antibiotics treat endocarditis prophylaxis?

The prophylactic antibiotic should be effective against viridans group streptococci. The guidelines recommend 2 grams of amoxicillin given orally as a single dose 30-60 minutes before the procedure as the drug of choice for infective endocarditis prophylaxis.

Can Corynebacterium cause hospital-acquired endocarditis?

Corynebacterium species are rarely reported as agents of hospital-acquired endocarditis. We describe three cases of endocarditis caused by three different species of corynebacteria in our hospital within an 18-month period, all associated with indwelling intravascular devices (IID).

Is there an evidence-based guideline for the antibiotic treatment of Corynebacterium striatum?

The aim of this study was to establish an evidence-based guideline for the antibiotic treatment of Corynebacterium striatum infections.

What are nondiphtherial corynebacteria?

When isolated from clinical specimens, nondiphtherial Corynebacteria, such as Corynebacterium striatum, Corynebacterium amycolatum, Corynebacterium minutissimum, Corynebacterium xerosis, and Corynebacterium freneyi, were originally thought to be contaminants [ 2

What is the focus of infection in infective endocarditis?

The focus of infection was often unknown, but IE was recognized in 8 episodes, all of which were prosthetic valve endocarditis (PVE) [4]. Corynebacterium pseudodipthteriticum, Corynebacterium jeikeium, and Corynebacterium striatumhave been acknowledged as important pathogens causing IE [5].

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