What is the meaning of chimeric gene?
Chimeric genes (literally, made of parts from different sources) form through the combination of portions of two or more coding sequences to produce new genes. These mutations are distinct from fusion genes which merge whole gene sequences into a single reading frame and often retain their original functions.
What does chimeric mean in biology?
(ky-MEER-ik) Having parts of different origins. In medicine, refers to a person, organ, or tissue that contains cells with different genes than the rest of the person, organ, or tissue.
What is a chimera in simple terms?
chimera, in genetics, an organism or tissue that contains at least two different sets of DNA, most often originating from the fusion of as many different zygotes (fertilized eggs). The term is derived from the Chimera of Greek mythology, a fire-breathing monster that was part lion, part goat, and part dragon.
What is chimerism in genetics?
A chimera is essentially a single organism that’s made up of cells from two or more “individuals”—that is, it contains two sets of DNA, with the code to make two separate organisms. One way that chimeras can happen naturally in humans is that a fetus can absorb its twin.
What is chimeric molecule?
A chimeric molecule is an engineered construct in which two or more components are linked to form a novel biological agent. This concept describes a bifunctional molecule in which one component targets the molecule to a specific cell and the second component exerts a pharmacological activity.
What is chimeric vector?
Chimeric viral vectors incorporate the favorable properties of two or more vectors, manipulating the advantages and disadvantages of each. Although not widely used at present, combining vector systems may assist in advancing specific gene therapy applications.
What are chimeric plants?
chimera, also spelled Chimaera, in botany, a plant or plant part that is a mixture of two or more genetically different types of cells. Thus in a chimera the components maintain their identity but are arranged in a definite pattern at the growing point.
What is chimera and Mosaic in animal reproduction?
An animal chimera is a single organism that is composed of two or more different populations of genetically distinct cells that originated from different zygotes involved in sexual reproduction. If the different cells have emerged from the same zygote, the organism is called a mosaic.
How does a chimeric individual form?
People that have two different sets of DNA are called human chimeras. It can happen when a woman is pregnant with fraternal twins and one embryo dies very early on. The other embryo can “absorb” its twin’s cells. It can also happen after a bone marrow transplant, and (in a smaller scale) during normal pregnancy.
What is chimeric read?
A chimeric read is a digital DNA sequence (i.e. a string of letters in a file that can be read as a DNA sequence) that originates from an actual chimera (i.e. a physical DNA sequence in a sample) or produced due to misreading the sample.
What is chimeric peptide?
chimeric peptides which are formed by the covalent coupling of a non- transportable peptide (e.g., P-endorphin) to a transportable peptide. that undergoes receptor- or absorptive-mediated transcytosis at the. BBB.
What does chimeric mean?
chi·mer·ic (kī-mĕr′ĭk, -mîr′-) adj. 1. Relating to or being an organism, part, or molecule that is a chimera: chimeric mice; chimeric proteins. 2. Relating to a monoclonal antibody produced from the cells of a nonhuman organism, usually a mouse, in which a portion of the antibody has been replaced with a human sequence of amino acids.
What does chimerical mean?
chimerical- being or relating to or like a chimera; “his Utopia is not as chimeric commonwealth but a practical improvement on what already exists”- Douglas Bush chimeral, chimeric 2. chimerical- produced by a wildly fanciful imagination; “his Utopia is not a chimerical commonwealth but a practical improvement on what already exists”- Douglas Bush
What is a chimeric virus?
This article is about the virus. For other uses, see Chimera. A chimera or chimeric virus is a virus that contains genetic material derived from two or more distinct viruses.