Can NSAIDs raise blood pressure?
All nonsteroidal antiinflammatory drugs (NSAIDs) in doses adequate to reduce inflammation and pain can increase blood pressure in both normotensive and hypertensive individuals [1]. The average rise in blood pressure is 3/2 mmHg but varies considerably [2-4].
Which NSAIDs cause hypertension?
Among nonselective NSAIDs, ibuprofen increases the risk of hypertension and stroke. Diclofenac does not increase the risk of hypertension, but does increase the risk of stroke. Naproxen (Naprosyn) does not increase the risk of hypertension or stroke.
Why should NSAIDs be avoided in hypertension?
NSAIDs also inhibit the vasodilating effects of prostaglandins and the production of vasoconstricting factors—namely, endothelin-1. These effects can contribute to the induction of hypertension in a normotensive or controlled hypertensive patient.
Do NSAIDs affect blood pressure medication?
Nonsteroidal anti-inflammatory drugs (NSAIDs) can induce an increase in blood pressure (BP) and may potentially reduce the efficacy of several antihypertensive drugs.
Can I take ibuprofen if I have high blood pressure?
NSAIDs help ease pain and inflammation. But if you have high blood pressure, heart failure, or kidney disease, you should not take an NSAID. And you should not take any drugs that have ibuprofen or another NSAID in them.
How much does naproxen raise BP?
Mean 24-hour systolic BP increased by 3.7 mmHg in ibuprofen users and by 1.6 mmHg in naproxen users, and it decreased by 0.3 mmHg in celecoxib users. Among people with normal baseline BP, hypertension developed in significantly more ibuprofen users (23.2%) than users of naproxen (19.0%) or celecoxib (10.3%).
Can you take ibuprofen if you have high blood pressure?
What should you not take with blood pressure medicine?
Some common types of OTC medicines you may need to avoid include:
- Decongestants, such as those that contain pseudoephedrine.
- Pain medicines (NSAIDs), such as ibuprofen and naproxen.
- Cold and flu medicines.
- Some antacids and other stomach medicines.
- Some herbal remedies and dietary supplements.
Which NSAID has the lowest cardiovascular risk?
Current evidence suggests that naproxen, a nonselective NSAID, is associated with the lowest risk of cardiovascular events. Therefore, naproxen is the NSAID of choice in patients with high cardiovascular risk.
Can I take naproxen if I have high blood pressure?
Do not use naproxen sodium if you have high blood pressure, unless your doctor has said that it’s safe. Naproxen sodium can also impair the effectiveness of common blood pressure medicines like ace inhibitors (such as Lotensin, Capoten, and Vasotec) and beta blockers (such as Coreg, Lopressor, and Corgard.)
What antiinflammatory can I take if I have high blood pressure?
Over-the-counter Tylenol (generic acetaminophen) is often the best choice for people with high blood pressure, heart failure, or kidney problems. However, high doses of Tylenol can damage the liver, so take the lowest dose you can to get enough pain relief. Never take more than 4,000 milligrams (mg) a day.
What medications to avoid with high blood pressure?
Do all NSAIDs raise blood pressure?
Several randomised studies have demonstrated that various nonsteroidal anti-inflammatory drugs (NSAIDs) elevate blood pressure in normotensive and hypertensive individuals; however, these data have been contradicted by numerous negative studies.
Do NSAIDs increase BP?
Most antihypertensive medications seem to have decreased effects with concomitant NSAID administration, with the exception of calcium channel blockers. Given the current literature, it appears that NSAIDs increase blood pressure in patients with controlled-hypertension, but the quantity of this increase is variable.
Does Sudafed increase blood pressure?
While an effective nasal decongestant, Sudafed (pseudoephedrine) can potentially cause an increase in blood pressure due to how the medication works in our body. This is especially concerning in those that may have already have high blood pressure or other heart problems.
Does Advil increase your blood pressure?
This type of drug can cause an increase in blood pressure. Blood pressure typically returns back to baseline when the drug is stopped. For those who take ibuprofen (Advil) occasionally for a headache or muscle soreness, the temporary elevation in blood pressure is not significant.