What is xylazine injection used for?
Xylazine administration is used for sedation, anesthesia, muscle relaxation, and analgesia. It causes a significant reduction in blood pressure and heart rate in healthy volunteers.
How is xylazine given?
Xylazine can be administered intravenously, intramuscularly, subcutaneously or orally. The commercial product contains 23.32 mg/ml xylazine hydrochloride in water based injectable solution. Xylazine can be obtained also as pure crystalline powder.
What class of drug is xylazine?
Xylazine is a sedative drug that also has muscle relaxant and central nervous system depressant properties. Chemically, it is similar to phenothiazine, an antipsychotic class of drugs that treats serious mental health disorders like schizophrenia.
How much xylazine can I give my cat?
Xylazine is usually administered in a clinic or hospital setting. For sedation in dogs and cats, xylazine is dosed at 0.25 to 0.5 mg per pound (0.5 to 1 mg/kg) intravenous or 0.5 to 1 mg per pound (1 to 2 mg/kg) intramuscular or subcutaneous.
Why is xylazine not used in humans?
Xylazine is not a controlled substance; it is marketed as a veterinary drug and used as a sedative, analgesic and muscle relaxant. In humans, it could cause central nervous system depression, respiratory depression, bradycardia, hypotension, and even death.
Can humans use xylazine?
Xylazine in humans may have similarly sedative effects as in animals. However, it is not designed nor safe for human consumption. Xylazine overdose is considered to be poisonous, causing hypotension, severe respiratory depression, bradycardia, a comatose state, and possibly death.
How long does xylazine last?
Duration of xylazine sedation and analgesia is dose dependent, generally lasting about 30 to 40 minutes following IV administration in standing or laterally recumbent patients. In dorsally recumbent patients the duration of enhanced cooperation provided by IV xylazine may be as short as 20 minutes.
Is xylazine toxic to humans?
Xylazine is not a controlled substance; it is marketed as a veterinary drug and used as a sedative, analgesic and muscle relaxant. In humans, it could cause central nervous system depression, respiratory depression, bradycardia, hypotension, and even death. Most of the non-fatal cases required medical intervention.
What drug reverses xylazine?
Tolazine is the antidote for xylazine and is administered to reverse affects.
Can you reverse xylazine?
Tolazine is the antidote for xylazine and is administered to reverse affects. Essential for completing surgical procedure.
Why xylazine is not given in cats?
Xylazine hydrochloride, an α2-adrenergic agonist known for its sedative and analgesic effects, is noted to induce vomiting in cats, particularly when administered via subcutaneous or intramuscular routes; however, the drug’s effects can be reversed effectively with an α-adrenoreceptor antagonist such as yohimbine.
What is the side effects of xylazine?
The most common side effects in humans associated with xylazine poisoning include bradycardia, respiratory and CNS depression, hypotension, and other changes in cardiac output.
What is xylazine HCl injection 20 mg?
Xylazine HCl Injection 20 mg/mL Dosage And Administration. Xylazine HCl Injection (xylazine) has been used successfully as a preanesthetic agent for pentobarbital sodium, thiopental sodium, thiamylal sodium, nitrous oxide, ether, halothane and methoxyflurane anesthesia.
When to use xylazine HCl injection in dogs and cats?
Xylazine HCl Injection (xylazine) should be used in dogs and cats when it is desirable to produce a state of sedation accompanied by a shorter period of analgesia. Xylazine HCl Injection (xylazine) has been used successfully as follows:
How many mg of propylparaben are in 20 mg of xylazine?
Each mL contains 20 mg Xylazine (base equivalent), 0.9 mg methylparaben, 0.1 mg propylparaben, water for injection; citric acid and sodium citrate for pH adjustment to 5.5 ± 0.3. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
When to give xylazine to a dog for sedation?
Xylazine HCl Injection (xylazine) should be used in dogs and cats when it is desirable to produce a state of sedation accompanied by a shorter period of analgesia. Xylazine HCl Injection (xylazine) has been used successfully as follows: 1.