What will be CSF findings in tuberculous meningitis?

What will be CSF findings in tuberculous meningitis?

Characteristic cerebrospinal fluid (CSF) findings of TBM include a lymphocytic-predominant pleiocytosis, elevated protein, and low glucose. CSF acid-fast smear and culture have relatively low sensitivity but yield is increased with multiple, large volume samples.

Can TB be detected in CSF?

Mycobacterium tuberculosis (M. tuberculosis) DNA can be detected in CSF using polymerase chain reaction (PCR). However, due to a high rate of false-positive results and exacting experimental conditions, PCR is unlikely to be widely used in underdeveloped areas.

What is MDR TB resistant to?

Multidrug-resistant TB (MDR TB) is caused by an organism that is resistant to at least isoniazid and rifampin, the two most potent TB drugs. These drugs are used to treat all persons with TB disease.

What is tuberculosis meningitis?

Tuberculous Meningitis (TBM) is a form of meningitis characterized by inflammation of the membranes (meninges) around the brain or spinal cord and caused by a specific bacterium known as Mycobacterium tuberculosis. In TBM, the disorder develops gradually.

How common is drug-resistant TB?

According to the report, approximately 20% of TB cases globally are estimated to be resistant to at least one of the first- or second-line anti-TB drugs, and 5% are resistant to both isoniazid and rifampicin, the most powerful and commonly used antibiotics in first-line treatment.

Can drug-resistant TB cured?

In most cases, TB is treatable and curable; however, people with TB can die if they do not get proper treatment. Sometimes drug-resistant TB occurs when bacteria become resistant to the drugs used to treat TB. This means that the drug can no longer kill the TB bacteria.

How do you get tuberculosis meningitis?

How TB meningitis is caused. Tuberculosis bacteria enter the body by droplet inhalation i.e. breathing in bacteria from the coughing/sneezing of an infected person.